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That still happens, to a degree

This is followed by the release of nesfatin-1 which stimulates cholecystokinin secretion leading to a rise in bile salts from gallbladder emptying, and the binding of Takeda P protein coupled receptor 5 (TGR5) onto the surface of the enteroendocrine cells, all of which eventually culminates in GLP-1 secretion [9]

Vitamin B12 enhances these effects by contributing to the production of red blood cells and improving oxygen delivery throughout the body, which supports endurance and energy expenditure

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10.1038/nm.3902 83 LovisaS.Fletcher-SananikoneE.SugimotoH.HenselJ.LahiriS.HertigA.et al (2020)